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CAR-T- a new perspective on immunotherapy

Iwona Urbanowicz, Iiwona Bil-Lula WIĘCEJ

Herbal resources in the medication of depression during pandemic COVID-19

Izabela Bolesławska, Natasza Bolesławska-Król, Klaudia Kowalska, Patrycja Dadyńska, Juliusz Przysławski WIĘCEJ

Comparative HPLC-DAD analysis of arbutin content in selected commercial spices from Lamiaceae available on the European market

Anna Magiera, Izabela Rychlińska, Monika A. Olszewska WIĘCEJ

Comparative study to assess the greenness of four analytical methods for simultaneous estimation of lamivudine, zidovudine, and nevirapine in pure form and pharmaceuticals using HPLC

Dibya Sundar Panda, S. K. Patro, Nabil K. Alruwaili,, Nasser Hadal Alotaibi, Ibrahim A. Naguib,, Eman Y. Santali, Della Grace Thomas Parambi, Mohammed Gamal WIĘCEJ

Daily facial skin care formulations: Benefits and risks

Tamara Attard, Lilian M. Azzopardi, Everaldo Attard WIĘCEJ

A rapid, simple and reliable RP-HPLC method for the determination of phenyramidol HCl in tablet dosage form

Funda Simsek, Nagehan Sarracoglu, Asuman Aybey, Doganay, Onur Pinarbasli WIĘCEJ

Pharmacokinetic assessment of the hepatic and intestinal firstpass effect of S-adenosylmethionine in rats

Tingting Yao, Lili Zhu, Jiajia Wang, Chunxia Lu, Yuan Su, Haiming Fang, Lijiu Zhang WIĘCEJ

Cardiovascular evaluation of the chemical structure of N-methyl piperazinyl phthalazine analogues

Nobuharu Yamaguchi , Kristof Biniecki, Christopher K. Jankowski, Lech Ciszewski WIĘCEJ

Novel 2,3-dihydro-1H-imidazo[2,1-a]isoquinolin-4-ium salts: synthesis, antitumor and antibacterial activity

Lifei Zhu, Shuhao Qu, Xiaoli Wang, Hui Huang, Huijuan Li, Lijie Zuo WIĘCEJ

Impact of dams’ diet on the levels of magnesium and zinc in the incisors of offspring rats

Adrian Podkowa, Dawid Gawliński, Kinga Gawlińska, Bożena Muszyńska, Włodzimierz Opoka WIĘCEJ

Upregulation of microrna-335 abrogates bone loss in arthritic ovariectomized mice via inhibition of RANKL-mediated FASN/ ERα signaling pathway

Li Shen, Wei Ren, Haibo Li, Baoshan Xu WIĘCEJ

The investigation of possible beneficial effects of gabapentin on adverse cardiac effects of high dose zoledronic acid: an experimental study

Anil Gulcu, Ozgur Akkaya WIĘCEJ

Effects of morin on sepsis induced acute lung injury by modulation of JNK dependent autophagic pathway through NF‑κB signaling pathways

Wei Wang, Jing Li, Yajing Zhang WIĘCEJ

Effect of lutein on oxidants and proinflammatory cytokinerelated liver ischemia-reperfusion injury

Betül Gündoğdu, Hakan Gökalp Taş, Bahadir Süleyman, Renad Mamedov, Neslihan Yüce, Ufuk Kuyrukluyıldız, Halis Süleyman WIĘCEJ

Analysis of the factors influencing consumer behavior in choosing of OTC medicines

Petković Staša, Milovanović Olivera, Dragutinović Ninoslava, Djurić Sonja, Pavlović Radiša, Ravić Marko, Kostić Marina, Petrović Marko, Tomović Marina, Djurić Dušan WIĘCEJ

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Professional responsibility of the pharmacist in the Polish legal system

Rafał Patryn, Mariola Drozd WIĘCEJ

Study on the plasma protein binding of liquiritin by ultrafiltration

Shu-Shu Wang, Tong-Juan Tang, Meng Zhang, Peng Zhou, Jin-Ling Huang WIĘCEJ

Effect of pharmaceutical care on the treatment of neuropathic pain induced by bone metastasis of liver cancer: case report

Qin Zhou, Zhiqiang Du , Shushan Wang, Hui Wang, Haohao Zhu PhD, Ying Jiang WIĘCEJ

β-lactam analogs of oxetanocins – synthesis and biological activity

Iwona E. Głowacka, Magdalena Grabkowska-Drużyc, Liwia Lebelt, Graciela Andrei, Dominique Schols, Robert Snoeck, Dorota G. Piotrowska WIĘCEJ

The quality of cold-pressed edible argan oil available on the European market

Małgorzata Dobrzyńska, Grzegorz Kosewski, Ilona Górna, Magdalena Kowalówka, Sławomira Drzymała-Czyż, Juliusz Przysławski WIĘCEJ

Bioactivity of extracts of European Lamium species on cytokine secretion from human neutrophils and peripheral blood mononuclear cells

Wioleta Wieczorkowska, Piotr Michel, Sylwia Zielińska, Katarzyna Dos Santos Szewczyk, Christian Zidorn, Monika E. Czerwińska WIĘCEJ

Arginase inhibitory properties of phenolic compounds from Rhodiola tangutica

Shan Wang, Meiduo Huayu, Shanshan Su, Xingmei Nan, Dejun Zhang, Dianxiang Lu, Zhanqiang Li WIĘCEJ

Development of extended-release formulation based on the quality by design approach

Kateryna Tarapon, Oksana Tryhubchak WIĘCEJ

Assessment of the moisturizing potential of a two-phase topical care product containing vegetable oils, glycerin, panthenol and sodium hyaluronate - a preliminary studies

Radosław Jerzy Balwierz, Paweł Biernat, Natalia Schafer, Dominik Marciniak, Anna Krzeszewska-Zaręba, Urszula Skotnicka-Graca, Anna Kurek-Górecka WIĘCEJ

Design of IR780 ethosomes for imaging and photodynamic photothermal therapy of infections

Mine Silindir-Gunay, Fidan Gulcin Onaral, Didem Kart WIĘCEJ

Effects of nifedipine combined with labetalol on serum leukemia inhibitory factor, apelin and oxidative stress indexes in patients with early-onset preeclampsia

Yu Chen, Yuxia Shi, Yixin Yang, Yu Chen, Yun Liu, Ying Gu WIĘCEJ

Baicalein suppresses LPS-induced inflammation by modulating nucleocytoplasmic transport of NF-κB p65 in macrophages

Ping Li, Jianran Hu, Baozhong Shi WIĘCEJ

Crystal structure of 8-(4-methylphenyl)-3-(propan-2-yl)-7,8-dihydroimidazo[2,1-c][1,2,4]triazin-4(6H)-one: a potential antitumor agent

Liliana Mazur, Renata Łyszczek, Małgorzata Sztanke, Krzysztof Sztanke WIĘCEJ

Survey on Patients’ opinions and preferences concerning the use of the Internet Patient Account in Poland: a preliminary report

Natalia Wrzosek, Agnieszka Zimmermann, Łukasz Balwicki WIĘCEJ

New tool to improve the adherence of psychiatric patients during hospitalization via combining a comprehensive medication review and education interview by a clinical pharmacist

Ivana Taskova, Jana Michalcova, Jan Saloun WIĘCEJ

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Resveratrol and its analogs: natural ampk agonists for the prevention and treatment of Alzheimer’s disease

Jia-Zhi Peng, Jian-Jun Liu WIĘCEJ

An evaluation of the potential impact of cherry flavor on the stability of montelukast tablets

Mariusz Staśkiewicz, Michał Nowicki, Klaudia Majewska, Justyna Nadajczyk, Aleksandra Rogut, Kamila Czarnecka, Paweł Szymański WIĘCEJ

Freshwater fish consumption in the prevention of diseases

Konrad Mielcarek, Katarzyna Socha WIĘCEJ

New voltammetry sensor for antipsychotic drug –mirtazapine based on glassy carbon electrode cover with carbon black nanoparticles

Martyna Ławrywianiec, Joanna Smajdor, Beata Paczosa-Bator, Robert Piech WIĘCEJ

HPLC fingerprint combined with multivariate statistical analysis for discrimination of coptis chinensis rhizome and fibrous root

Jiuhua Song, Fan Wu, Zhigang Yi, Qiong Tang, Kai Shi WIĘCEJ

A novel CDK4/6 inhibitor WXJ-111, against breast cancer through mediated cell-cycle arrest and apoptosis

Jing Ji, Jing Feng, Gang Pan, Ming-Xiao Lv, Jin-Yu Lv, Wen-Wen Liu, Xing-Bei He, Wen-Lian Tang, Qi-Lan Qian, Zhen Zhang, Yu-Xin Xu, Meng-Ru Xie, Dan-Dan Xia, Yu Bao, Xiu-Jun Wang, Jin-Ming Ma, Bin Liu WIĘCEJ

Diversified biological activity of (1→3),(1→4)-α-D-glucan from mango (Mangifera indica L.) fruits

Roman Paduch, Mateusz Pięt, Kamila Wlizło, Iwona Wertel, Anna Pawłowska, Sylwia Trojnar, Ewa Sajnaga, Waldemar Kazimierczak, Marcin Skowronek, Adrian Wiater WIĘCEJ

Selected parameters of the health quality of young shoots of white and red headed cabbage

Joanna Kapusta-Duch, Adam Florkiewicz, Teresa Leszczyńska, Renata Bieżanowska-Kopeć WIĘCEJ

Effect of nimesulide against indomethacin-induced oxidative liver damage in rats

Canan Tuz Yilmaz, Bahadir Suleyman, Renad Mammadov, Adalet Ozcicek, Seval Bulut, Gulce Naz Yazic, Mine Gulapoglu, Halis Suleyman WIĘCEJ

Lignan matairesinol illustrates anti-diabetic effect via inhibition of DPP-4 and hepato-protective effect via inhibition of apoptosis in diabetic rats

Liu Yang, Chunlian Wang WIĘCEJ

The metabolic conversion of metamizole (dipyrone) in male and female patients after total gastrectomy for stomach cancer

Edyta Szałek, Arkadiusz Spychała, Patrycja Kozanecka, Hanna Urjasz, Tomasz Grabowski, Anna Wolc, Elżbieta Długosz, Witold Kycler, Edmund Grześkowiak, Agnieszka Karbownik WIĘCEJ

A possible protective effect of the plasma PCSK9 against myocardial hypertrophy and diastolic dysfunction

Natalia Pauli, Violetta Dziedziejko, Krzysztof Safranow, Michał Rać, Dariusz Chlubek, Tadeusz Sulikowski, Monika Ewa Rać WIĘCEJ

The effects of ranolazine on cobalt chloride-induced chemical hypoxia in endothelial cells

Edip G. Cekic, Gurkan Yigitturk, Melike O. Onal, Hulya Elbe, Nesrin F. Basaran, Feral Ozturk WIĘCEJ

The effect of low-dose inhaled fluticasone propionate on fractional exhaled nitric oxide in asthmatic pediatric patients with and without allergic rhinitis

Marek Biesiadecki, Sabina Galiniak, Marta Rachel, David Aebisher WIĘCEJ

Opinions of pharmacists in poland on changes in professional competencies due to the COVID-19 pandemic

Joanna Oberska, Anna M. Dworakowska, Małgorzata Kozłowska-Wojciechowska WIĘCEJ

Acknowledgement to Reviewers 2021

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Improved medication adherence with smart applications and medication dispensers – a literature review

Hanna Keidong, Daisy Volmer WIĘCEJ

Development and validation of the analytical methods for the determination of bromhexine hydrochloride and related impurities in novel orodispersible tablets

Mirosław Strózik, Magdalena Strzebońska, Katarzyna Skiba, Wiktor Tatara WIĘCEJ

TLC-densitometric identification of valproic acid

Wioletta Parys, Alina Pyka-Pająk WIĘCEJ

Cell viability and collagen metabolism of MCF-7 breast cancer cells are affected by carbon monoxide released from CORM-2

Magdalena Maria Sawicka, Paweł Drągowski, Joanna Stelmaszewska, Izabela Prokop, Karol Sawicki, Barbara Polityńska, Wojciech Miltyk WIĘCEJ

Hypoxia Inducible Factor-1α promotes the therapeutic effect of Astragaloside IV on hypertension

Cijing Cha, Shufang Wang, Yiling Hou WIĘCEJ

Platelet-rich plasma counteracts interleukin-1 induced inhibition of collagen biosynthesis through the recovery of impaired β1-integrin signaling and prolidase activity in human skin fibroblasts

Tomasz Guszczyn, Magda Chalecka, Adam Kazberuk, Ilona Ościłowska, Jerzy Pałka, Arkadiusz Surażyński WIĘCEJ

Synthesis and antidepressant-like activities of some piperidine derivatives: involvements of monoaminergic and opioidergic systems

Ceren Kaya, Nazli Turan Yucel, Ummuhan Kandemir, Derya Osmaniye, Ozgur D. Can, Umide Demir Ozkay WIĘCEJ

The effect of carvacrol on tramadol-induced oxidative renal injury in rats: biochemical and histopathological evaluation

Alparslan Koc, Ufuk Kuyrukluyildiz, Ali Caner Sayar, Mustafa Gazi, Bahadir Süleyman, Renad Mammadov, Nergis Akbaş, Remzi Arslan, Halis Süleyman, Bülent Yavuzer WIĘCEJ

Development and evaluation of colon-specific releasing nanoemulsion/hydrogel pellets of camptothecin

Zheng Xu, Huijuan Lv, Yun Li, Guoyu Qiu, Yudong Wang, Jianing Zhang, Zengkui Zhang, Zhigang Yang, Yingqian Liu, Yanbin Shi WIĘCEJ

Release of salicylic acid from new multiphase bases with consideration of the preparation method

Lucyna Bułaś, Beata Szulc-Musioł, Wioletta Siemiradzka, Małgorzata Służalec, Barbara Dolińska WIĘCEJ

Artificial neural networks and their application in the optimization of carbamazepine solid dispersion

Tanja Vojinovic, Zorica Potpara, Mihailo Vukmirovic, Nemanja Turkovic, Svetlana Ibric WIĘCEJ

An insight of FDA-approved drugs for the management of aging-related disorder – a in silico study

Tong-Jie Yang, Quan-Qing Wan, Peng-Peng Wen WIĘCEJ

Exposure to non-opioid analgesics during pregnancy and the risk of adverse drug reactions

Katarzyna Karlowicz-Bodalska, Anna Prochera, Adrianna Rogowska, Agata Muszyńska, Natalia Sauer, Ernest Kuchar, Krystyna Głowacka, Anna Wiela-Hojeńska WIĘCEJ

On the spacer group effect on anti-Escherichia coli activity of cationic gemini surfactants using molecular connectivity indices and atomic charges

Anna Mozrzymas WIĘCEJ

Permissibility of the off-label use of a medicinal product in the context of a doctor’s liability – an attempt at clarification of the issue under the Polish law

Krzysztof Kozłowski, Waldemar Wierzba, Bogusław Machaliński WIĘCEJ

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Application of GC-MS and LC-MS techniques for direct analysis of amines in pharmaceutical substances

Elżbieta Stolarczyk, Aleksandra Groman, Marta Zezula, Anna Witkowska WIĘCEJ

Application of chemometric methods for determination the lipophilicity of pentacyclic triterpene derivatives

Katarzyna Bober-Majnusz, Ewa Bębenek, Elwira Chrobak, Monika Kadela-Tomanek WIĘCEJ

Evaluation of the proteomic profile in patients with celiac disease and malabsorption syndrome

Paulina Gulbicka, Dagmara Pietkiewicz, Eliza Matuszewska, Szymon Plewa, Jan Matysiak, Marian Grzymisławski, Zenon J. Kokot WIĘCEJ

Evaluation of the cariogenicity of prebiotic (1→3)-α-D-glucooligosaccharides

Paulina Adamczyk, Marta Kinga Lemieszek, Ewa Ozimek, Małgorzata Pleszczyńska, Marcello Locatelli, Marek Siwulski, Anna Sroka-Bartnicka, Adrian Wiater WIĘCEJ

Synthesis and structural characterization of novel 2-pyrazoline derivatives: Evaluation of their antiproliferative activity and fluorescence properties

Zefine Ugras, Fatih Tok, Emine Salva, Gozde Ultav, Bedia Kocyigit-Kaymakcioglu WIĘCEJ

Awareness and knowledge of drug-food interactions among polish third-age university listeners before and after training - a questionnaire study

Agnieszka Wiesner, Paweł Zagrodzki, Paweł Paśko WIĘCEJ

Chlorogenic acid improves diabetes-associated muscular atrophy in mice

Liu Xianchu, Liu Ming WIĘCEJ

Study on dissolution behavior in vitro of an osteoporosis treatment drug: eldecalcitol soft capsule

Dan Liang, Zelian Chen, Lan Su, Jian Zhang, Zhifeng Chen WIĘCEJ

Composition development and in vitro evaluation of O/W emulsions based on natural emulsifier Olivem 1000 as tea tree oil carriers

Magdalena Wróblewska, Katarzyna Winnicka WIĘCEJ

The effect of carvacrol upon experimentally induced diabetic neuropathy and neuropathic pain in rats

Bilge Ekinci, Bahadir Suleyman, Renad Mammadov, Arzu Gezer, Ali Sefa Mendil, Nergis Akbas, Seval Bulut, Cagatay Nusret Dal, Halis Suleyman WIĘCEJ

In silico and in vivo investigation of the neuroprotective benefits of ketamine against isoflurane-induced cognitive impairment

Shenghui Luan, Praveen Thaggikuppe Krishnamurthy WIĘCEJ

Community pharmacist-driven interventions in COPD: improving knowledge, attitude and health status

Milica D. Ćulafić, Milena M. Kovačević, Marija N. Jovanović, Maša I. Roganović, Sandra D. Vezmar Kovačević, Katarina M. Vučićević, Branislava R. Miljković WIĘCEJ

The importance of using inflammatory biomarkers and scoring systems in early assessment of severity and outcome of acute pancreatitis treatment

Olivera Marinkovic, Sladjana Trpkovic, Ana Sekulic, Aleksandra Ilic, Aleksandar Pavlovic, Barbara Loboda, Vesna Grbovic, Zeljko Todorovic, Stefan Simovic, Natasa Zdravkovic WIĘCEJ

Pharmacoeconomic aspects of hospital treatment of facial fractures - cost of illness study based on data from Balkan country with recent history of social and economic transition

Jana V. Desnica, Marina J. Kostić, Slobodan M. Janković, Sara S. Mijaliović, Olivera Z. Milovanović, Katarina D. Parezanović Ilić, Dejan D. Vulović WIĘCEJ

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Food preparation methods contribution to skin aging: a systematic review

Mila Filipovic, Danijela Pecarski, Jelena Djordjevic, Marina Ivanovic, Vladimir Ilic, Milica Lukic WIĘCEJ

Temozolomide: a cytostatic drug that is still important today

Agata Czarnywojtek, Kamil Dyrka, Magdalena Borowska, Jeremi Kościński, Jakub Moskal, Nadia Sawicka-Gutaj, Agnieszka Lewandowska, Stefaan Van Gool, Marta Fichna, Paweł Gut, Patryk Graczyk, Krzysztof Pietrończyk, Marzena Dworacka WIĘCEJ

Midostaurin – the first targeted therapy drug for patients with acute myeloid leukaemia with FLT3 mutation

Aneta Nowicka, Edyta Szałek, Lidia Gil, Martin Sima, Agnieszka Karbownik WIĘCEJ

Korean and siberian pine: review of chemical composition and pharmacological profile

Milica V. Nikolic, Vladimir Lj. Jakovljevic, Jovana V. Bradic, Marina T. Tomovic, Branislav P. Petrovic, Anica M. Petrovic WIĘCEJ

Validated HPLC-UV method for determination of venlafaxine and its metabolite – O-desmethylvenlafaxine in human plasma

Iwona Szlaska, Tomasz Pawiński, Monika Kukiełka, Kinga Zuzanna Kośnik WIĘCEJ

Optimization of chromatographic systems for detection and determination of carbamazepine in pharmaceutical formulations, serum, and saliva by HPLC-DAD

Karol Wróblewski, Izabela Dybała, Anna Petruczynik, Małgorzata Szultka-Młyńska, Daria Janiszewska, Joanna Róg, Hanna Karakuła-Juchnowicz, Dariusz Juchnowicz, Bogusław Buszewski WIĘCEJ

Quantitative chirality in the binding of androgens to their receptors

Piotr F.J. Lipiński, Jan Cz. Dobrowolski, Anna Baraniak WIĘCEJ

Acetylcholinesterase inhibitors:  structure–activity relationship and kinetic in vitro studies on selected flavonoids

Katarzyna Jakimiuk, Diana Nazaruk, Michał Tomczyk WIĘCEJ

In vivo evaluation of the antipsoriatic effect of hydrogel with lavandin essential oil and its main components after topical application

Katarzyna Sosnowska, Monika Tomczykowa, Katarzyna Winnicka, Danuta Kalemba, Michał Tomczyk WIĘCEJ

In vitro dissolution test of ketoprofen: development and evaluation of release from soft and hard gelatine capsules

Katarzyna Karłowicz-Bodalska, Tomasz Han, Natalia Sauer, Wojciech Szlasa, Olga Szczepańska, Natalia Janicka, Katarzyna Wacławczyk, Ernest Kuchar, Anna Wiela-Hojeńska WIĘCEJ

Formulation, characterization, and in vitro evaluation release nimesulide from different rectal suppository bases

Beata Szulc – Musioł, Lucyna Bułaś, Barbara Dolińska WIĘCEJ

Study of glycopyrrolate dry powder behavior in new single dose inhalers under generic product development

Jakub Strzemieczny, Bogusława Musiał, Agnieszka Pawlaczyk, Małgorzata Sznitowska, Danuta Siluk WIĘCEJ

Preparation and characterization of fast-release oral film formulation containing ondansetron hydrochloride solid dispersion

Ting Wei, Ya Zhao, Zhongxi Zhao WIĘCEJ

Effect of silymarin on the parameters of oxidative stress in hearts in the course of diabetes mellitus in wistar rats

Piotr Bramora, Maria Zych, Weronika Borymska, Ilona Kaczmarczyk-Żebrowska WIĘCEJ

A combination of simvastatin and low-protein diet increases renal 2-oxoglutarate dehydrogenase activity in rats

Małgorzata Belczyk, Malgorzata Knapik-Czajka, Anna Gawedzka, Katarzyna Mikolajczyk, Jagoda Drag WIĘCEJ