TABLE OF CONTENTS

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The QSAR anałysis of tricyclic non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Elżbieta Brzezińska WIĘCEJ

Structure and biological activity of some 4-amino-3-cinnoline-carboxylic acid derivatives. QSAR analysis of cinnoline derivatives with antibacterial properties.

Elżbieta Brzezińska, AniJrzej Stańczak, Zbigniew Ochocki WIĘCEJ

Sludies on estrification and sulphonation of riboflavin in the environment of highly concentrated sulphuric acid.

Wojciech Pająk, Elżbieta Brzezińska WIĘCEJ

Kinetics of diitiazem hydrochloride in solid phase.

Izabela Muszalska, Maciej Siąkowski WIĘCEJ

Technology of eye drops containing aloe (Aloe arborescens Mill. - Liliuceae) and eye drops containing both aloe and neomycin sulphate.

A. Kodym, A. Marcinkowski, H. Kukuła WIĘCEJ

Synthesis and biological action of 3-R-4-substituted-2-l,2,4-triazoline-5-thione.

Maria Dobosz, Monika Wujec, Adam Waśko WIĘCEJ

Synthesis, characterization and antimicrobial activity of some mixed ligand Co(II) and Ni(II) complexes.

Vitthal S. Shivankar, Narendra V. Takkar WIĘCEJ

Facile synthesis of fused pyrazolo[1,5-a]pyrimidinepyrazolo[1,5-a]triazines and N-sulphonamidopyrazoles as antiinflammatory.

O.A. Fathalla, M.E.A. Zaki, S.A. Swelam, S.M. Nofal, W.I. El-Eraky WIĘCEJ

Synihesis of new N-substituted cyclic imides with an expected anxiolytic activity. XVI. Derivatives of l-acetoxy-7,7-dimethyl-bicyclo[2.2.2]octan-5-one-2,3-dicarboximide.

Jerzy Kossakowski, Elżbieta Hejchman WIĘCEJ

Synthesis and biological activity of certain novel derivatives of lH-pyrrolo[l,2-c][ l,3]thiazine.

Tadeusz S. Jagodziński. Aneta Wesołowska, Elżbieta Jagodzińska, Sławomir Rump WIĘCEJ

Synthesis and antibacterial properties of 4-sulfonamidopyrimidine derivatives.

Jerzy Cieplik. Janusz Pluta. Olaf Gubrynowicz WIĘCEJ

Qualitative and quantitative chromatographic investigation of flavonoids in Pyrus communis L. flowers.

Izabela Rychlińska, Jan Gudej WIĘCEJ

FIavonoid compounds from the flowers of Cirsium rivulare (Jacq.) All.

Jolanta Nazaruk, Jan Gudej WIĘCEJ

Phenolic acids from Symphoricarpos albus (E.) Blake (Caprifoliaceae).

Mirosława Szaufer-Hajdrych, Grażyna Zgórka WIĘCEJ

Chemoprevention of cancerogenesis - the role of sulforaphane.

Ewa Sotowiej, Teresa Kasprzycka-Guttman, Piotr Fiedor, Wojciech Rowiński WIĘCEJ

Quantification of P2/Gene expression in Caco-2 cells treated with sodium bulyrate using real-time reverse tran-scription - PCR (RT-PCR) assay.

Arkadiusz Orchel, Izabella Molin, Zofia Dzierżewicz, Małgorzata Latocha, Ludmiła Węglarz, Tadeusz Wiłczok WIĘCEJ

The effect of sulphasalazine and its metabolites on the colonic epithelial Caco-2 cells.

Arkadiusz Orchel, Beata Parfiniewicz, Jolanta Lodowska, Zofia Dzierżewicz, Ludmiła Węglarz, Tadeusz Wilczok WIĘCEJ

Phosphate prodrugs of isophosphoramide mustard.

Konrad Misiura, Daria Szymanowicz, Joanna Wietrzyk, Adam Opolski WIĘCEJ

Methods for the assessment of quality and stability of azidocillin.

Żyta Płotkowiak, Maria Popielarz-Brzezińńska, Monika Serafin WIĘCEJ

Practical use of DD-Peptidase 64-575 for the assay ot inhibition activity of natural and synthetic -lactam com-pounds.

Jolanta Sołecka, Robert Łysek, Bartłomiej Furman, Marek Chmielewski, Wiesław Kurzątkowski WIĘCEJ

New carbocyclic lexitropsins with dinitromustard as N-terminal fragment. Inhihition of topoisomerases.

Agnieszka Markowska, Anna Bielawska, Krzysztof Bielawski, Krystyna Midura-Nowaczek WIĘCEJ

Stability of mycophenolic acid in plasma samples from patients during mycophenolate mofetii therapy.

Tomasz Pawiński, Leslie M. Shaw WIĘCEJ

Application of the rough sets theory in structure activity relationship of antielectrostatic ammonium compounds.

Jerzy Krysiński, Andrzej Skrzypczak, Grzegorz Demski WIĘCEJ

Molecular structure of some 3-amino-2-oxazolidinone derivatives.

Jerzy Krzywda, Jacek Cybulski, Anna E. Kozioł, Zdzisław Chilmonczyk WIĘCEJ

Preliminary evaluation of CNS effects of 6-O-substituted chelidonine derivatives.

Ewa Jagietło-Wójtowicz, Anna Chodkowska, Maria Gadzikowska, Ewa Chojecka-Koryn, Grzegorz Gryn- kiewicz WIĘCEJ

Liposomal formulation of idarubicin.

Piotr Slifir.ski, Wiesław Szelejewski, Grzegorz Grynkiewicz, Jerzy Gubernator, Arkadiusz Kozubek WIĘCEJ

A study on the stereochemical purity of trandolapril and octahydro-lH-indole-2-carboxylic acid by HPLC method.

Iwona Cendrowska, Krzysztof Bańkowski, Joanna Iskra-Jopa WIĘCEJ

Synthesis, physicochemical properties and biological activity of 2,6-disubstituted 7-methylpurines and the 7,9-dialkyl analogues.

Alicja Kowalska, Jolanta Sochacka WIĘCEJ

Synthesis, immunological activity and theoretical study of new 5-substituted 3-methylisoxazole[5,4-d] l ,2,3-triazin-4-one derivatives.

Marcin Maczynski, Aneta Jezierska, Michał Zimecki, Stanisław Ryng WIĘCEJ

Photo- and radiostability of some l ,4-dihydropyridine derivatives in the solid state.

Barbara Marciniec, Magdalena Ogrodowczyk WIĘCEJ

Polymeric membranę electrodes for selective determination of methiaden.

Hanna Hopkata, Joanna Drozd, Dorota Kowalczuk, Agata Artymiak WIĘCEJ

Kinetics of hydrolysis of diitiazem hydrochloride in aqueous solutions.

Izabella Muszalska, Leszek Jamszoł, Dariusz Grześkowiak WIĘCEJ

Feasibility of the Ph. Eur. flow-trough cell for dissolution testing of the compounded rectal suppositories con-taining indomethacin or sodium diclofenac.

Brunon Woyczikowski, Małgorzata Sznitowska, Stanisław Janicki Janusz Pilichowski, Agnieszka Urbańska WIĘCEJ

Antimicrobial studies of hydrazone complexes of Hg(II) and Fe(II) divalent metal ions.

K.J. Donde, V.R. Patil, S.P. Malve WIĘCEJ

Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XXIV. Derivatives of N-hydroxy-1 -methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboxymide.

Jerzy Kossakowski, Mariola Krawiecka WIĘCEJ

Synthesis of new N-substituted cyclic imides with potential anxiolytic activity. XXV. Derivatives of halo-genodibenzole[e.h.]bicyclo[2.2.21octane-2.3-dicarboximide.

Jerzy Kossakowski, Mirosław Perliński WIĘCEJ

Antioxidant properties of captopril in vitro.

Anna Radomska WIĘCEJ

Determination of immunological activity in vitro of some plant raw materials.

Janina Drozd, Elżbieta Anuszewska WIĘCEJ

Influence of felbamate on the antiociceptive action of morphine, metamizol and indomethacin in mice.

Wanda Pakulska, Irena Wejman, Elżbieta Czarnecka WIĘCEJ

Studies on brain biogenic amines in methanolic extract of cuscuta reflexa Roxb. and Corchorus olitorius Linn. Seed treated mice.

Malaya Gupta, Upal Kanti Mazumder, Dilikupmar Pal, Shiladitya Bhattacharya, Sumit Chakrabarty WIĘCEJ

New possibilities of application of multifunctional polymers and polymer conjugates

Janusz Pluta, Bożena Karolewicz WIĘCEJ

Selenium as an anticancerogenic agent

Anna Wojtczak WIĘCEJ

The synthesis and applications of 5-aminolevulinic acid (ALA) derivatives in photodynamic therapy and photo-diagnosis.

Zbigniew Dąbrowski, Mirosław Kwaśny, Jarosław Kamiński, Maria Bełdowicz, Lidia Lewicka, Bożena Obukowicz, Miron Kaliszewski, Ewa Pirożyńska WIĘCEJ

Search for new lead structures in the isoxasole heterocyclic system.

Stanisław Ryng, Michał Zimecki, Adam Fedorowicz, Aneta Jezierska, Tadeucz Głowiak WIĘCEJ

The optima! way from laboratory to industrial facility.

Ludwik Synoradzki WIĘCEJ

A semi-micromethod for determination of oxalate in human plasma.

Tadeusz Porowski, Władysław Gałasiński WIĘCEJ

Hydrolysis of N- and S-monomethyl derivatives of 2-thiophenobarbital.

Monika Tarsa, Grzegorz Żuchowski, Jacek Bojarski WIĘCEJ

Hydrolysis of N,N- and N,S-dimethyl derivatives of 2-thiophenobarbital.

Monika Tarsa, Grzegorz Żuchowski, Jacek Bojarski WIĘCEJ

Interaction of thioridazine with ocular melanin in vitro.

Ewa Buszman, Renata Różańska WIĘCEJ

Alteration of growth and metabolic activity of cells in the presence of' propranolol and metoprolol.

Jolanta Lodowska, Adam Wilczek, Irena Tam, Beata Cwalina, Longina Swiatkowska, Tadeusz Wilczek WIĘCEJ

Comparative kinetics of azathioprine and metazathioprine mercaptolysis in presence of physiological thiols.

Maria Chrzanowska, Agnieszka Hałas, Marta Kuehn, Tadeusz Hermann WIĘCEJ

Search for substances with antioxidant and antiamnestic activitics among 2-substituted 4-(3H)-quinazolones.

Sergey Kovalenko, Igor Belenichev, Vladislav Nikitin, Aleksandr Karpenko WIĘCEJ

A synthesis of 3,6,17 -trihydroxy-5-pregnan-20-one(triolone) from 3,6 -dihydroxy-5-pregnan-20-one (diolone).

Witold Mazurkiewicz WIĘCEJ

Synthesis and evaluation of substituted naphthalimide nitrogen mustards as rationally - designed anticancer compounds.

A. Pain, S. Samanta, S. Dutta, A.K. Saxena, M. Shanmugavel, H. Kampasi, G.N.Qazi, U. Sanyal WIĘCEJ

Synthesis and antiproliferative activity in vitro of new 3-substituted aminoisoxazolo[5,4-b]pyridines.

Krystyna Poręba, Joanna Wietrzyk, Adam Opolski WIĘCEJ

Improving the O/W emulsifying properties of rapeseed lecithin ethanol insoluble fraction by acetylation.

Marian Sosada, Beata Pasker, Marzena Bogocz WIĘCEJ

Qualitative and quantitative chromatographic invesligation of hydroquinone derivatives in Pyrus communis L. flowers.

Izabela Rychlińska, Jan Gudej WIĘCEJ

Kaempferol and quercetin głycosides from Rubus idaeus L. leaves.

Jan Gudej WIĘCEJ

Chemical and toxicological evaluation of methanol extract of Cuscuta reflexa Roxb. stem and Corchorus olito-rius Linn. Seed on hematological parameters and hepatorenal functions in mice.

Upal Kanti Mazumder, Malaya Gupta, Dilipkumar Pal, Shiladitya Bhattacharya WIĘCEJ

A comparison of chromatographic separation of selected nicotinic acid derivatives by TLC and HPLC tech-niques.

Alina Pyka, Józef Sliwiok, Anna Niestrój WIĘCEJ

Qualitative and quantitative analysis of three amino acid derivatives of anticonvulsant activity.

Elżbieta Pirianowicz-Chaber, Anna Goidnik, Ryszard Paruszewski WIĘCEJ

Rapid and simple high-performance liquid chromatographic determination of felbamate in serum.

Beata Paw, Genowefa Misztal and Robert Skibiński WIĘCEJ

Validation of a method for simultaneous determination of menthol and methyl salicylate in pharmaceuticals by capillary gas chromatography with cool on-column injection.

Jan Krzek, Janusz Sławomir Czekaj, Włodzimierz Rzeszutko WIĘCEJ

The Third Multidisciplinary Conference on Drug Research, Piła 2002. Effects of l ,25-dihydroxyvitamin D, and some putative steroid neuroprotective agents on the hydrogen perox-ide-induced damage in neuroblastoma-glioma hybrid NG108-15 cells.

Magdalena Tetich, Monika Leśkiewicz, Bogusława Budziszewska, Agnieszka Basta-Kaim, Andrzej Kutner, Władysław Lasoń WIĘCEJ

Evaluation of the mutagenic activity of phenolics from the bark of Yucca Schidigera Roezl.

Hanna Czeczot, Małgorzata Podsiad, Michał Skrzycki, Anna Stochmal, Wiesław Oleszek WIĘCEJ

Studies on the influence of vitamin D, metabolites on apoptosis induction in human neoplastic cellls.

Beata M. Gruber, Elżbieta L. Anuszewska WIĘCEJ

Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XXII. Derivatives of l-methoxy-5-bicyclo[2.2.2]-oct-5-one-2,3-dicarboximide.

Jerzy Kossakowski, Monika Jarocka-Wierzba WIĘCEJ

Synthesis and antiaggregatory activity of RGD-peptidomimetics based on 4-oxo-4-(piperazine-l-yl)butyric acid as Arg-mimetic.

Sergei A. Andronati, Andrei A. Krysko, Vladimir M. Kabanov, Tatyana A. Kabanova, Tamara L. Karaseva, Boris M. Chugunov, Svetlana B. Meshkova, Zoya M. Topilova WIĘCEJ

Synthesis, physico-chemical and anticonvulsant properties of some N-substituted amides of 3-pirocycloalkylpyrrolidine-2,5-dione.

Jolanta Obniska, Alfred Zejc WIĘCEJ

The furanocoumarins in the roots of Heracleum sibiricum L.

Anna Bogucka-Kocka, Tadeusz Krzaczek WIĘCEJ

Variability in the content and composition of essential oil from lemon balm (Melissa officinalis L.) cultivated in Poland.

Jolanta Patora, Teresa Majda, Józef G6ra, Barbara Klimek WIĘCEJ

Non-antibiotics-drugs with additional antimicrobial activity.

Stefan Tyski WIĘCEJ

Analytical studies and application of reaction of promazine and thioridazine hydrochlorides with some oxidants.

Helena Puzanowska-Tarasiewicz, Joanna Karpińska WIĘCEJ

Analytical application of the reaction.s of amitriptyline with eriochrome cyanine R and pyrocatechol violet.

Barbara Starczewska, Anna Jasińska WIĘCEJ

Capillary electrophoresis with a diamine EOF modifier as an approach for glutaminę dipeplide containing for-mulations.

Małgorzata Jaworska, Małgorzata Wilk, Zofia Szulińska WIĘCEJ

Kinetics of degradation of cefetamet pivaloyloxymethyl ester and its hydrochloride in solid phase.

Anna Jelińska, Marianna Zając, Leszek Dobrowol.ski, Beata Medenecka, Piotr Ruciński, Irena Oszczapowicz WIĘCEJ

Thc stability of quinapril hydrochloride - a mixture of amorphous and crystalline forins (QHCl-AC) - in solid phase.

Beata Stanisz WIĘCEJ

Synthesis and biological action of l-substituted-3-R-4-phenyl-2l,2,4-triazoline-5-thione.

Monika Wujec, Monica Pitucha, Maria Dobosz, Urszula Kosikowska, Anna Malm WIĘCEJ

Synthesis and antiinflammatory activity of some 2-arylamino-2-thiazoline-4-ones.

Roman Lesyk, Boris Zimenkovsky, Ivanna Subtelna, Igor Nektegayev, Gennadij Kazmirchuk WIĘCEJ

The effect of the Melissa officinalis extract on immune response in mice.

Janina Drozd, Elżbieta Anuszewska WIĘCEJ

Flavonoids in the leaves of Asciepias incarnata L.

Maria Sikorska WIĘCEJ

Preliminary evaluation of anticonvulsant activity of some 4-(benzyloxy)-benzamides.

Henryk Marona, Edward Szneler WIĘCEJ

Evaluation of psychopharmacological effects of petroleum ether extract of Cuscuta reflexa Roxb. stem in.

Pal Dihpkumar, Panda Chinmay, Sinhababu Samir, Dutta Arnab, Bhattacharya Shiladitya WIĘCEJ

The Synthesis and antibacterial activity of 3-alkyl derivatives of some pyrimido[4,5-d] pyrimidine.

Jerzy Cieplik, Janusz Pluta, Olaf Gubrynowicz WIĘCEJ