Compaction - renaissance of a method of dry granulation powders. Roller compaction is a modern method of dry granulation. Powder is fed through two rotating rollers, where is submitted high stress to the formation of compact. Elimination of water and binder solution permit improvement stability of API (active pharmaceutical ingredient) and solid dosage form. Received granulate has good mechanical strength. Roller compactor innovation and optimization critical parameters, such as for example powder feed rate, permit improvement quality of the product and increase throughput of the process.

Keywords: compaction, dry granulation, powders.