Krzysztof Paluch, Lidia Tajber
Zarys metod charakterystyki fizykochemicznej układów amorficznych produkowanych metodą suszenia rozpyłowego
2009-03-25
Amorphous systems can be produced deliberately or unintentionally during various technological processes. Spray drying is one the most widespread methods of manufacturing of amorphous systems. Calorimetric methods, dynamic vapour sorption, spectroscopy and X-ray diffraction constitute a basic analytical set-up used for qualitative and quantitative characterisation of disordered materials. Additionally, to enable detailed description of surface and bulk characteristics, isothermal microcalorimetry, inverse gas chromatography or nuclear magnetic resonance may be employed. Modern quality standards require accurate quantification of disorder in the finished product to minimise manufacture issues and batch to batch variations of the medicines.
Zarys metod charakterystyki fizykochemicznej układów amorficznych produkowanych metodą suszenia rozpyłowego
344.38 kB |
21 grudnia 2017