II. Development of pulmonary drug delivery technologies

In Part II of this review, modi cation of chemical structure of substance i. e. prodrug approach, conjugation substance with macromolecules and methods for enhancing drug absorption from the lung have been investigated. Viable and recent strategies to accelerate drug transport across respiratory epithelia or to decrease the rate of local degradation processes are reported. In this part have been described innovation in DPI, MDI and nebulization.