Chengdong Wu, Ghulam Murtaza, Muhammad Arfat Yameen, Muhammad Naeem Aamir, Muhammad Akhtar, Aboul Malik, Yuhao Zhao

Permeation study through bacterial cellulose membrane.
2014-03-27

The objective of this study was to fabricate topical formulations of diclofenac diethylamine (DD)
using isopropyl myristate (IPM) and isopropyl palmitate (IPP) as permeation enhancers. Franz cell and bacterial cellulose were used as analytical instrument and diffusion membrane, respectively. Permeation enhancers exhibited significant effect on the permeation characteristics of DD. It was concluded from the results that improved permeation of DD was observed when IPP was used as enhancer.
Keywords: bacterial cellulose, permeation, transdermal drug delivery