PRZEGLĄD NUMERÓW / TABLE OF CONTENTS

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Organic solvents in the pharmaceutical industry.

Katarzyna Grodowska, Andrzej Parczewski WIĘCEJ

Analytical methods for residual solvents determination in pharmaceutical products.

Katarzyna Grodowska, Andrzej Parczewski WIĘCEJ

The stability of N-[2-(4-o-fluorophenylpiperazin-1-yl)ethyl]-2.5-dimethyl-1-phenylpyrrole-3,4-dicarboxamide in aqueous-organic solutions.

Marianna Zając, Agnieszka Sobczak, Wiesław Malinka, Aleksandra Redzicka WIĘCEJ

Exploring the antiperoxidative potential of morin on cyclophosphamide- and flutamide-induced lipid peroxida-tion and changes in cholesterol profile in rabbit model.

Supratim Ray, Partha Chowdhury, Bibhas Pandit, Sabrani Dey Ray, Sumit Das WIĘCEJ

Synthesis and in vitro antimicrobial study of Schiff base and thiazolidinone of 1-cyclopropyl-6-fluoro-7-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-quinolone.

Navin B. Patel, Sarvil D. Patel WIĘCEJ

Microwave assisted synthesis of some novel 2-pyrazoline derivatives as possible antimicrobial agents.

Rakesh Chawla, Ujjwal Sahoo, Anshu Arora, Prabodh Chandler Sharma, Vijayaraj Radhakrishnan WIĘCEJ

Synthesis and anti-inflammatory activity of some novel biphenyl-4-carboxylic acid 5-(arylidene)-2-(aryl)-4- oxothiazolidin-3-yl amides.

Aakash Deep, Sandeep Jain, Prabodh Chander Sharma WIĘCEJ

Immunostimulalory activity of Calophyllum Brasiliense, Ipomea pes-caprae and Matayba elaeagnoides demon-strated by human peripheral blood mononuclear cells proliferation.

Marina Elisa Philippi, Bruna Mom Duarte, Carolina Vieira da Silva, Michel Thomaz de Souza, Rivaldo Niero, Valdir Cechinel Filho, Edneia Casagranda Bueno WIĘCEJ

Immunostimulatory effetss of extract of Pulicaria crispa before and after Schisostoma mansoni infection.

Amany S. Maghraby, Nagwa Shalaby, Howida I. Abd-Alla, Samia A. Ahmed, Hussein M. Khaled, Mahmoud M. Bahgat WIĘCEJ

Anti-inflammatory activity of aqueous fruit pulp extract of Hunteria umbellata K. Schum in acute and chronic inflammation.

Ighodaro Igbe, Fidelis P. Ching, Aigbe Eromon WIĘCEJ

Evaluation of aqueous preparations from herbal drugs.

Zuzana Vitková, Bronislava Brázdovičová, Katarína Ralbovská, Andrea Halenárová WIĘCEJ

Testing lyoequivalency for three commercially sustained-release tablets containing diltiazem hydrochloride.

Hamzah A. Maswadeh, Othman A. Al-Hanbali, Reem A. Kanaan, Ashok K. Shakya, Anwar Maraqa WIĘCEJ

Influence of humidity and hydroxypropyl cellulose, hydroxypropyl-methyl cellulose, gliceryl behenate or mag-nesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase.

Beata Stanisz, Sylwia Paszun, Natalia Strzyżycka, Emil Ptaszyński WIĘCEJ

Tableting of floating pellets with verapamil hydrochloride: Influence of type of tablet press.

Wiesław Sawicki, Rafał Łunio WIĘCEJ

The wound healing activity of flower extracts of Punica granatum and Achillea kellalensis in Wistar rats.

Abdollah Ghasemi Pirbalouti, Abed Koohpayeh, Iraj Karimi WIĘCEJ

Antidiabetic potential of medicinal plants.

Neelesh Malviya, Sanjay Jain, Sapna Malviya WIĘCEJ

Determination of stability constants and acute toxicity of potential hepatotropic gadolinium complexes.

Elżbieta Mikiciuk-Olasik, Emilia Wojewoda, Ireneusz Bilichowski, Małgorzata Witczak, Bolesław Karwowski, Małgorzata Wągrowska-Danilewicz, Olga Stasikowska WIĘCEJ

NMR and gas chromatography studies of lyophilized human brain tumors.

Ryszard Marszałek, Maciej Pisklak, Wiesław Jankowski, Jacek Łukaszkiewicz, Dariusz Horsztyński, Iwona Wawer WIĘCEJ

Identification and determination of antihypertonics from the group of angiotensin convertase inhibitors by densi-tometric method in comparison with HPLC method.

Elżbieta Wyszomirska, Krystyna Czerwińska, Aleksander P. Mazurek WIĘCEJ

Effect of 1,2,3,4,6-penta-O-galloyl--D-glucose on elastase and hyaluronidase activities and its type II collagen expression.

Song-Ja Kim, Sandesh A. Sancheti, Shruti S. Sancheti, Byung-Hun Um, Seon-Mi Yu, Sung-Yum Seo WIĘCEJ

Optimization of aripiprazole synthesis.

Andrzej Leś, Katarzyna Badowska-Rosłonek, Marta Łaszcz, Agata Kamieńska-Duda, Piotr Baran and Łukasz Kaczmarek WIĘCEJ

Novel 6,8-dibromo-4-(3H)quinazolinone derivatives of promising anti-inflammatory and analgesic properties.

Mohamed S. Mosaad, Kamel M. Mohsen, Kassem M.M. Emad, Nageh Abotaleb, Nofal M. Salwa, Ahmed F. Marwa WIĘCEJ

Formulation and characterization of a cream containing extract of fenugreek seeds.

Muhammad K. Waqas, Naveed Akhtar, Mahmood Ahmad, Ghulam Murtaza, Haji M.S. Khan, Muhammad Iqbal, Akhtar Rasul, Naveed S. Bhatti WIĘCEJ

Hypolipidemic effect of ethanolic extract from the leaves of Hibiscus sabdariffa L. in hyperlipidemic rats.

Sandeep Gosain, Raghuveer Ircchiaya, Prabodh Chander Sharma, Suresh Thareja, Atin Kalra, Aakash Deep, Tilak Raj Bardwaj WIĘCEJ

The effect of binders on the bioavailability of ofloxacin tablets in animal model.

Fatima Rasool, Mahmood Ahmad, Haji M.S. Khan, Naveed Akhtar, Ghulam Murtaza WIĘCEJ

Coated capsules for drug targeting to proximal and distal part of human intestine.

Kateřina Dvořáčková, Miloslava Rabišková, Jan Gajdziok, David Vethý, Jan Muselík, Jurga Bernatoniene, Martina Bajerová, Pavlína Drottnerová WIĘCEJ

Cytotoxic activity of e-aminocaproylamino acids in breast cancer MCF-7 and fibroblast cell lines.

Krystyna Midura-Nowaczek, Agnieszka Markowska, Dorota Krajewska, Sławomir Wołczyński WIĘCEJ

Selected aspects of europeization of pharmaceutical law.

Agnieszka Zimmermann, Lubomira Wengler, Leszek Pawłowski WIĘCEJ

Synthesis and biological studies of novel 9(10H)-acridone derivatives.

Amit Girdhar, Sandeep Jain, Neelam Jain, Shikha Girdhar WIĘCEJ

Kinetic modeling on drug release from controlled drug delivery systems.

Suvakanta Dash, Padala .Narasimha Murthy, Lilakanta Nath, Prasanta Chowdhury WIĘCEJ

Mechanism of solvolysis of N-[2(4-o-fluorophenylpiperazin-1-yl)ethyl-2,5-dimethyl-1-phenylpyrrole-3,4-dicarboxamide (PDI).

Agnieszka Sobczak, Marianna Zając, Wiesław Malinka, Aleksandra Redzicka WIĘCEJ

Studies of the degradation mechanism of pyrrolo[3,4-c]pyridine-1,3(2H)-dione derivatives with analgesic activ-ity: isolation and identification of products and summary.

Izabela Muszalska WIĘCEJ

Synthesis, characterization and antimicrobial evaluation of some new 1,3-thiazole-2,4-diamine derivatives.

Nadeem Siddiqui, Shaquiquizzaman, Mujeeb Ur Rahman, M. Faiz Arshad, Waquar Ahsan, M. Shamsher Alam, Sharique Ahmed WIĘCEJ

Synthesis of novel 1,3,4-oxadiazole derivatives as potential antimicrobial agents.

Rakesh Chawla, Anshu Arora, Manoj Kumar Parameshwaran, Prabodh Chander Sharma, Sukumar Michael, Thengungal Kochupappy Ravi WIĘCEJ

Design and biological evaluation of biphenyl-4-carboxylic acid hydrazide-hydrazone for antimicrobial activity.

Aakash Deep, Sandeep Jain, Prabodh Chander Sharma, Prabhakar Verma, Manesh Kumar, Chander Prakash Dora WIĘCEJ

New 4,6-diacetyl resorcinol Mannich bases: synthesis and biological evaluation.

Mohammed Sardaryar Khan, Asif Husain, Sanjay Sharma WIĘCEJ

Synthesis and microbial studies of (4-oxothiazolidinyl)sulfonamides with quinazolin-4(3H)ones moiety.

Navin B. Patel, Virendra N. Patel, Hemant R. Patel, Faiyaz M. Shaikh, Jaymin C. Patel WIĘCEJ

Effects of a novel antiinflammatory polyherbal preparation (Sudershanam oil) on hematological parameters in Wistar rats.

Chintan D. Patel, Vandana D. Modi, Bhaswat S. Chakraborty, Neeta Mathuria, Paresh Dadhaniya, Prasad A. Borade, Pravin Morankar WIĘCEJ

Development and characterization of nanoparticles of glibenclamide by sovent displacement method.

Chander Prakash Dora, Shailendra Kumar Singh, Sanjeev Kumar, Ashok Kumar Datusalia, Aakash Deep WIĘCEJ

Formulation and in vitro evaluation of floating microballons of indomethacin.

Peeyush Bhardwaj, Himanshu Chaurasia, Deepti Chaurasia, Sunil K. Prajapati, Shobhna Singh WIĘCEJ

Formulation of two-drug controlled release non-biodegradable microparticles for potential treatment of muscles pain and spasm and their simultaneous spectrophotometric estimation.

Shujaat A. Khan, Mahmood Ahmad, Ghulam Murtaza, Muhammad N. Amir, Naveed Akhtar, Rozina Kousar WIĘCEJ

Evaluation of oleo-gum resin as directly compressible tablet excipient and release retardant.

Pradeep Kumar, Inderbir Singh WIĘCEJ

Studies on in vitro antiplasmodial activity of Cleome rutidosperma.

Anindya Bose, Peter J. Smith, Carmen A. Lategan, Jayanta Kumar Gupta, Sudam Si WIĘCEJ

Photostabilization of papaverine hydrochloride solutions.

Karolina Piotrowska, Tadeusz W. Hermann, Alicja Pawelska WIĘCEJ

Assay of tolnaftate in human skin samples after in vitro penetration studies using high performance liquid chromatography

Toma Keţutytë, Olga Kornyšova, Audrius Maruška, Vitalis Briedis WIĘCEJ

Comparative analysis of pharmaceuticals and dietary supplements containing extracts from the leaves of Gingko biloba L.

Anna Gawron-Gzella, Paulina Marek, Justyna Chanaj, Irena Matławska WIĘCEJ

The influence of ciprofloxacin on hamster ovarian cancer cell line CHO AA8.

Tomasz Kloskowski, Joanna Olkowska, Aybars Nazlica, Tomasz Drewa WIĘCEJ

Sulfonamides of 2-[(2,6-dichlorophenyl)amino]phenylacetoxy-acetic acid and their antibacterial studies

Navin B. Patel, Jignesh N. Patel, Jaydeep D. Lilakar WIĘCEJ

Synthesis and biological activity of some novel pyrazolines.

S. Venkataraman, Saras Jain, Kamal Shah, Neeraj Upmanyu WIĘCEJ

New potential renin inhibitors with dipeptide replacement in the molecule.

Iwona Winiecka, Jadwiga Dudkiewicz-Wilczyńska, Iza Roman, Ryszard Paruszewski WIĘCEJ

Synthesis and in vitro antibacterial activity of thymol and carvacrol derivatives.

Chandra S. Mathela, Krishna K. Singh, Vivek K. Gupta WIĘCEJ

Anti-clastogenic activity of Azadirachta indica against benzo[a]pyrene in murine forestomach tumorigenesis bioassay.

Subhash Chander Gangar, Rajat Sandhir, Ashwani Koul WIĘCEJ

Evaluation of in vitro antioxidant potential of aqueous extract of Trapa natans L. fruits.

Neelesh Malviya, Sanjay Jain, Avnish Jain, Sourabh Jain, Rajenda Gurjar WIĘCEJ

Separation of an aqueous extract Inonotus obliquus (chaga). A novel look at the efficiency of its influence on proliferation of A549 human lung carcinoma cells.

Witold Mazurkiewicz, Katarzyna Rydel, Dariusz Pogocki, Marta Kinga Lemieszek, Ewa Langner, Wojciech Rzeski WIĘCEJ

Development and characterization of Eudragit RS 100 loaded microsponges and its colonic delivery using natu-ral polysaccharides.

Vikas Jain, Ranjit Singh WIĘCEJ

Evaluation of anti-compulsive effect of methanolic extract of Benincasa hispida Cogn. fruit in mice.

Shikha Girdhar, Manish M. Wanjari, Sunil K. Prajapati, Amit Girdhar WIĘCEJ

Novel chromenimidazole derivatives as antifungal compounds: synthesis and in vitro evaluation.

Suresh Thareja, Arunima Verma, Atin Kalra, Sandeep Gosain, Prarthana V. Rewatkar, Ganesh R. Kokil WIĘCEJ

Bioanalytical method development and validation for the simultaneous estimation of lamivudine and stavudine in human plasma by HPLC.

Surajpal Verma, Pooja Mullick, Md. Sleem Bhatt, Nadeem Siddiqui, Ozair Alam, Indu Bala, Suroor A. Khan WIĘCEJ

Analysis of hypotensive compounds occurring in complex agents.

Mariusz Stolarczyk, Anna Maślanka, Anna Apola, Jan Krzek WIĘCEJ

Methods of chromatographic determination of medicines decreasing the level of cholesterol.

Elżbieta Kublin, Barbara Kaczmarska-Graczyk, Ewa Malanowicz, Aleksander P. Mazurek WIĘCEJ

Determination of active substances in multicomponent veterinary preparations of antiparasitic action by HPLC method.

Wanda Białecka, Anna Kulik WIĘCEJ

Luminescence method for the determination of lorazepam in tablets.

Ganna Anelchyk, Darya Aleksandrova, Georgii Malzev, Inna Leonenko, Alla Yegorova WIĘCEJ

Determination of retinyl palmitate in ointment by HPLC with diode array detection.

Anna Kwiecień, Urszula Hubicka, Jan Krzek WIĘCEJ

Application of thin-layer chromatography for the quality control and screening the free radical scavenging activ-ity of selected pharmaceutical preparations containing Salvia officinalis extract.

Łukasz M. Cieśla, Monika Waksmundzka-Hajnos WIĘCEJ

Effect of nicotinamide and its two derivatives on the generation of reactive oxygen species in human monocytes cooperating with platelets.

Jacek Międzobrodzki, Grzegorz Łach, Roman Jaworek, Tomasz Panz WIĘCEJ

Synthesis and structure-activity relationship analysis of new olivacine derivatives.

Beata Tylińska, Ryszard Jasztold-Howorko, Henryk Mastalarz, Dagmara Kłopotowska, Beata Filip, Joanna Wietrzyk WIĘCEJ

Synthesis and anticonvulsant evaluation of some novel 2,5-substituted 1,3,4-thiadiazoles: pharmacophore model studies.

Harish Rajak, Chinmay Kumar Behera, Rajesh Singh Pawar, Praadep Kumar Singour, Murli Dhar Kharya WIĘCEJ

Wound healing activity of Malva sylvestris and Punica granatum in alloxan-induced diabetic rats.

Abdollah Ghasemi Pirbalouti, Shahrzad Azizi, Abed Koohpayeh, Behzad Hamedi WIĘCEJ

Design, development and in vitro evaluation of metoprolol tartrate tablets containing xanthan-tragacanth.

Akhtar Rasul, Muhammad Iqbal, Ghulam Murtaza, Muhammad K. Waqas, Muhammad Hanif, Shu-jaat A. Khan, Naveed S.Bhatti WIĘCEJ

Effect of ritanserin and leuprolide alone and combined on marble-burying behavior in mice.

Uday Gaikwad, Milind Parle, Ashok Kumar, Dinanath Gaikwad WIĘCEJ

Vasorelaxation induced by amodiaquine in rat superior mesenteric arteries: in vivo and in vitro studies.

Oluwatosin A. Adaramoye, Monica M. Almeida WIĘCEJ

Antiarrhythmic activity of novel S-enantiomers of pyrrolidin-2-one derivatives with adrenolytic properties.

Jacek Sapa WIĘCEJ

Testosterone supplementation and prostate cancer, controversies still exist.

Tomasz Drewa, Piotr Chłosta WIĘCEJ

Self-medication in Hungary, from the perspective of pharmacy workers.

Csilla Major, Zoltán Vincze WIĘCEJ

Synthesis, antituberculostatic, antifungal and antibacterial activities of 3-substituted phenyl-6-substituted phenyl-1,2,4-triazolo[4,3-b] pyridazines.

Mojahidul Islam, Anees A. Siddiqui WIĘCEJ

New cinnamyl ester and polyalcohol derivative from the rhizomes of Curcuma oligantha var oligantha.

Shamim Ahmad, Mohammad Ali, Shadid H. Ansari WIĘCEJ

Synthesis and in vivo anticonvulsant evaluation of 2-chloroquinolinyl hydrazone derivatives.

Suresh Kumar, Sandhya Bawa, Sushma Drabu, Rajiv Kumar, Lalit Machawal WIĘCEJ

Editorial

Grzegorz Grynkiewicz WIĘCEJ

Preclinical drug development.

Teresa Brodniewicz, Grzegorz Grynkiewicz WIĘCEJ

Determination of total hypericins in St. John’s wort and herbal medicinal products.

Małgorzata Anyżewska, Anna Kowalczuk, Anna, Łozak, Renata Jabłczyńska, Zbigniew Fijałek WIĘCEJ

Determinations of impurities in medical products containing metformin hydrochloride.

Gabriela Kłaczkow, Elżbieta L. Anuszewska WIĘCEJ

Use of the hyphenated LC-MS/MS technique for characterization of the impurity profile of quetiapine during drug development.

Elżbieta U. Stolarczyk, Andrzej Kutner WIĘCEJ

The effect of a novel dinuclear platinum complex with berenil and 2-picoline ligands on growth of human breast cancer cells.

Krzysztof Bielawski, Anna Bielawska, Bożena Popławska, Arkadiusz Surażyński, Robert Czarnomysy WIĘCEJ

Salivary aldehyde dehydrogenase activity – Influence of drugs intake, preliminary research.

Joanna Giebułtowicz, Piotr Wroczyński, Jacek Wierzchowski WIĘCEJ

Possible role of HSP60 in synergistic action of anthracyclines and sulindac in HeLa cells.

Beata M. Gruber , Jolanta Krzysztoń-Russjan, Irena Bubko, Elżbieta L. Anuszewska WIĘCEJ

Evaluation of the expression of metalloproteinases 2 and 9 and their tissue inhibitors in colon cancer treated with phytic acid.

Małgorzata Kapral, Joanna Wawszczyk, Magdalena Jurzak, Dominika Dymitruk, Ludmiła Węglarz WIĘCEJ

Inhibition of DNA topoisomerases I and II by G3 PAMAM-NH2 dendrimer – modified digoxin and proscil-laridin A conjugates in cell free system.

Katarzyna Winnicka, Anna Bielawska, Krzysztof Bielawski WIĘCEJ

Synthesis and proapoptotic properties of new casein kinase II inhibitors.

Mirosława Koronkiewicz, Magda Żukowska, Zdzisław Chilmonczyk, Andrzej Orzeszko, Zygmunt Kazimierczuk WIĘCEJ

Nitro-2-pyridyl-1-thioglucosides: application in synthesis of 5-analogues of glycosyltransferases natural sub-strates.

Gabriela Pastuch, Roman Komor, Marta Grec, Wiesław Szeja WIĘCEJ

Glycoconjugates, products of uridine derivatives phosphitylation and oxidation as glycosyltransferases potential inhibitors.

Marta Grec, Piotr Świerk, Gabriela Pastuch, Wiesław Szeja WIĘCEJ

The influence of paclitaxel on hydrolytic degradation in matrices obtained from aliphatic polyesters and polyes-ter carbonates.

Monika Musiał-Kulik, Janusz Kasperczyk, Katarzyna Jelonek, Piotr Dobrzyński, Katarzyna Gębarowska, Henryk Janeczek, Marcin Libera WIĘCEJ

Microsatellite marker analysis in the treatment and diagnosis of familial hypertrophic cardiomyopathy.

Sławomir Smolik, Dorota Domal-Kwiatkowska, Małgorzata Kapral, Ludmiła Węglarz WIĘCEJ

Development and validation of analytical procedure – control of residual 2-iodopropane in latanoprost.

Aleksandra Groman, Elżbieta U. Stolarczyk WIĘCEJ

Validated HPCL method for determination of cefuroxime in human plasma.

Anna Szlagowska, Michał Kaza, Piotr J. Rudzki WIĘCEJ

Tiamulin hydrogen fumarate – veterinary uses and HPLC method of determination in premixes and medicated feeding stuffs.

Dorota Krasucka, Agata Mitura, Wojciech Cybulski, Katarzyna Kos, Wojciech Pietroń WIĘCEJ

Proliferation and cellular death of A375 cell line in the presence of HDACs inhibitors.

Ewa Chodurek, Arkadiusz Orchel, Natalia Gawlik, Anna Kulczycka, Arkadiusz Gruchlik, Zofia Dzierżewicz WIĘCEJ

Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts.

Arkadiusz Gruchlik, Ewa Chodurek, Alicja Zajdel, Adam Wilczok, Ludmiła Węglarz, Zofia Dzierżewicz WIĘCEJ

Polyunsaturated fatty acids alter expression of genes encoding antioxidant enzymes in A549 cells exposed to doxorubicin.

Alicja Zajdel, Piotr Paduszyński, Arkadiusz Gruchlik, Joanna Głogowska-Ligus Adam Wilczok, Zofia Dzierżewicz WIĘCEJ

Transcriptional regulation of interleukin 6 and its receptor in colon cancer cells by phytic acid.

Małgorzata Kapral, Joanna Wawszczyk, Sławomir Smolik, Ludmiła Węglarz WIĘCEJ

Baicalin inhibits free radicals processes initiated by chromium ions.

Ewa Sawicka, Dorota Średnicka, Anna Długosz WIĘCEJ

Growth of human fibroblasts in the presence of 6-hydroxyhexanoic acid.

Arkadiusz Orchel, Katarzyna Jelonek, Janusz Kasperczyk, Zofia Dzierżewicz WIĘCEJ

The role of estradiol in reducing ethanol toxicity.

Anna Długosz, Anna Pruss, Jadwiga Lembas-Bogaczyk WIĘCEJ

Asymmetric synthesis of -N,N-dialkylamino alcohols by transfer hydrogenation of N,N-dialkylamino ketones.

Tomasz Kosmalski WIĘCEJ

Comparison of accelerated and real-time cyclosporine A release testing from poly(L-lactide-co-trimethylene carbonate) matrices.

Katarzyna Jelonek, Janusz Kasperczyk, Piotr Dobrzyński, Karolina Szczepka, Henryk Janeczek, Bożena Jarząbek, Joanna Jaworska, Anna Smola WIĘCEJ

An approach towards efficient peptide synthesis in aqueous solution.

Krzysztof Zając, Zbigniew J. Kamiński WIĘCEJ

Pharmacokinetic parameters of amoxicillin in pigs and poultry.

Dorota Krasucka, Cezary Jacek Kowalski WIĘCEJ

Examination of antimicrobial activity of selected non-antibiotic products.

Hanna Kruszewska, Tomasz Zaręba, Stefan Tyski WIĘCEJ

The role of amino acids supplementation of protective Na2H2EDTA containing ointments in chelation of aller-genic metal ions.

Sławomir Smolik, Paweł Nogaj, Agnieszka Szpakowska, Jolanta Lodowska, Ludmiła Węglarz WIĘCEJ